The main aim of the Bio Equivalence and Bio Availability-2019 is to promote the regulations related to Bio Equivalence and Bio Availability were put into place, considering the latest advances in the science. A significant role in the discovery, development, and regulation of new drug products involves in recent research of Bio Equivalence and Bio Availability. a crucial component of abbreviated new drug applications (ANDAs), leading to market access of safe, effective, and low cost in the advance studies of bioequivalence.